فوق دکترا درجراحی کلیه ومجاری ادرار ازدانشکده پزشکی دانشگاه تهران و عضو انجمن ارولوژی ایران
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كاربر میهمان خوش آمدید
Sat 16 Jul 2011

In The Name Of God

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The Books  That Authored And Translated by

Mohammad Hezarkhani

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ارسال شده توسط دکتر محمد هزارخانی در ساعت 3:32 بعد از ظهر
Sat 20 Sep 2014

 

L. Simon1, K. Murphy1, M.B. Shamsi1, L. Liu1, B. Emery1, K.I. Aston1, J. Hotaling1 and D.T. Carrell1,2,3,*1Andrology and IVF Laboratory, Department of Surgery (Urology), University of Utah, Salt Lake City, UT 84108, USA 2Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT 84108, USA 3Department of Human Genetics, University of Utah, Salt Lake City, UT 84108, USA /July 18, 2014.

STUDY QUESTION Does sperm DNA damage affect early embryonic development?

SUMMARY ANSWER Increased sperm DNA damage adversely affects embryo quality starting at Day 2 of early embryonic development and continuing after embryo transfer, resulting in reduced implantation rates and pregnancy outcomes.

WHAT IS KNOWN ALREADY Abnormalities in the sperm DNA in the form of single and double strand breaks can be assessed by an alkaline Comet assay. Some prior studies have shown a strong paternal effect of sperm DNA damage on IVF outcome, including reduced fertilization, reduced embryo quality and cleavage rates, reduced numbers of embryos developing into blastocysts, increased percentage of embryos undergoing developmental arrest, and reduced implantation and pregnancy rates.

STUDY DESIGN, SIZE, DURATION A cross-sectional study of 215 men from infertile couples undergoing assisted reproduction techniques at the University of Utah Center for Reproductive Medicine.

PARTICIPANTS/MATERIALS, SETTING, METHODS Sperm from men undergoing ART were analyzed for DNA damage using an alkaline Comet assay and classified into three groups: ‘low damage’ (0–30%), ‘intermediate damage’ (31–70%) and ‘high damage’ (71–100%). The cause of couples' infertility was categorized into one of the three types (male, female or unexplained). Each embryo was categorized as ‘good’, ‘fair’ or ‘poor’ quality, based on the number and grade of blastomeres. The influence of sperm DNA damage on early embryonic development was observed and classified into four stages: peri-fertilization effect (fertilization rate), early paternal effect (embryonic days 1–2), late paternal effect (embryonic days 3–5) and implantation stage effect.

MAIN RESULTS AND THE ROLE OF CHANCE The paternal effect of sperm DNA damage was observed at each stage of early embryonic development. The peri-fertilization effect was higher in oocytes from patients with female infertility (20.85%) compared with male (8.22%; P < 0.001) and unexplained (7.30%; P < 0.001) infertility factors. In both the early and late paternal effect stages, the low DNA damage group had a higher percentage of good quality embryos (P < 0.05) and lower percentage of poor quality embryos (P < 0.05) compared with the high DNA damage group. Implantation was lower in the high DNA damage (33.33%) compared with intermediate DNA damage (55.26%; P < 0.001) and low DNA damage (65.00%; P < 0.001) groups. The implantation rate was higher following blastocyst transfer (58.33%), when compared with early stage blastocyst (53.85%; P = 0.554) and cavitating morula transfers (34.40%; P < 0.001). Implantation was higher when the female partner age was ≤35 years when compared with >35 year age group (52.75 versus 35.44%; P = 0.008).

LIMITATIONS, REASONS FOR CAUTION A potential limitation of this study is that it is cross-sectional. Generally in such studies more than one variable could affect the outcome. Analyzing sperm is one part of the equation but a number of environmental and female factors also have the potential to influence embryo development and implantation. Furthermore, the selection of morphologically normal and physiologically motile sperm may result in isolation of sperm with reduced DNA damage. Therefore, selecting the best available sperm for ICSI may lead to experimental bias, as the selected sperm do not represent the overall sperm population in which the DNA damage is measured. Similar studies on selected sperm and with a larger sample size are now required.

WIDER IMPLICATIONS OF THE FINDINGS The paternal influence of damaged chromatin is more prominent after zygotic transcriptional activation. A prolonged paternal effect on the developing embryo may be due to the active repair mechanism present in oocytes that tends to overcome the damaged paternal chromatin. The probability of eliminating an embryo fertilized by a sperm with damaged DNA is higher at the blastocyst stage than the cleavage stage; therefore blastocyst transfer could be recommended for better implantation success. Finally, we recommend ICSI treatment for patients with a higher percentage of sperm with DNA damage as well as additional studies with a larger sample size aimed at assessing DNA damage analysis as a diagnostic tool for IVF.

STUDY FUNDING/COMPETING INTEREST(S) This work was supported by the University of Utah internal funds. The authors declare no competing interests.

Source:Human Reproduction 2014

ارسال شده توسط دکتر محمد هزارخانی در ساعت 10:47 قبل از ظهر |
Sat 20 Sep 2014

 

H. Utsuno, T. Miyamoto*, K. Oka and T. Shiozawa/Department of Obstetrics and Gynecology, Shinshu University, Matsumoto, Nagano, Japan August 7, 2014.

 

STUDY QUESTION How are protamine deficiencies associated with sperm head morphology in subfertile men?

SUMMARY ANSWER The prevalence of morphological variations and large nuclear vacuoles was slightly higher in protamine-deficient spermatozoa than in non-deficient spermatozoa.

WHAT IS KNOWN ALREADY A protamine deficiency was previously reported to be associated with an abnormal sperm morphology; however, how they are related to each other remains unclear. This is further confounded by a number of protamine-deficient spermatozoa having a normal head morphology.

STUDY DESIGN, SIZE, DURATION This is a cross-sectional study, including 36 men diagnosed with male factor infertility or participating in an assisted reproduction program. To assess sperm head morphology, this study analyzed 2400 spermatozoa with a protamine deficiency and 2400 spermatozoa with a normal protamine status. An additional 21 men were analyzed to examine DNA fragmentation and its relationship with protamine deficiencies and sperm head morphologies.

PARTICIPANTS/MATERIALS, SETTING, METHODS The morphology of the sperm head was evaluated based on its shape, size and nuclear vacuoles at a magnification of >6000×. Using elliptic Fourier analysis, the shape was summarized into four numeric variables. The protamine status was evaluated with chromomycin A3 (CMA3). Sperm head size, vacuoles and shape were compared between protamine-deficient and non-deficient spermatozoa. DNA fragmentation was evaluated with the terminal deoxynucleotidyltransferase-mediated dUTP nick-end labeling (TUNEL) assay. The percentages of protamine-deficient spermatozoa and DNA fragmentation were compared between spermatozoa with morphologically normal heads and those with abnormal heads.

MAIN RESULTS AND THE ROLE OF CHANCE Variations in head size (P < 0.0001) and shape (P < 0.0001) were significantly higher, with narrower (P < 0.001), more fan-shaped (P < 0.01) and more square-shaped forms (P < 0.001) in protamine-deficient spermatozoa than in non-deficient spermatozoa; however, the distribution of morphological variations markedly overlapped. Protamine deficiencies were more frequently observed in spermatozoa with large nuclear vacuoles than in those without them (32.0 ± 3.1 versus 39.4 ± 2.9%, P < 0.001). The percentage of protamine-deficient spermatozoa was significantly lower in spermatozoa with a normal head morphology than in those with an abnormal head morphology (25.4 ± 2.6 versus 38.0 ± 2.5%, P < 0.001). The percentage of DNA fragmentation was significantly higher in protamine-deficient spermatozoa than in non-deficient spermatozoa (11.3 ± 2.1 versus 1.6 ± 0.6%, P < 0.001), and was lower in spermatozoa with a normal head morphology than in those with an abnormal head morphology (2.6 ± 0.7 versus 6.4 ± 0.2%, P < 0.001).

LIMITATIONS, REASONS FOR CAUTION We were unable to discriminate the kind of protamines or quantify the extent of the protamine deficiency in spermatozoa using the CMA3 staining method.

WIDER IMPLICATIONS OF THE FINDINGS This study provided a novel insight into how abnormal protamination affects sperm head morphology as well as the relationship between sperm head morphology and its own molecular integrity. Our results will contribute to a deeper understanding of the benefits and limitations of the morphological selection of spermatozoa for ICSI.

STUDY FUNDING/COMPETING INTEREST(S) This study was supported by a JSPS Grant-in-Aid for the Encouragement of Scientists (25931009, 26931010). All authors have no conflicts of interest to disclose.

Source:Human Reproduction 2014

ارسال شده توسط دکتر محمد هزارخانی در ساعت 10:46 قبل از ظهر |
Sat 20 Sep 2014

 

1 Smoking and risk of low- and high-grade prostate cancer: Results from the REDUCE study Clinical Cancer Research, September 19, 2014   

 

2 Role of PSA density in diagnosis of prostate cancer in obese men International Urology and Nephrology, September 19, 2014    

 

3 Cabazitaxel remains active in patients progressing after docetaxel followed by novel androgen receptor pathway targeted therapies Full Text European Urology, September 19, 2014    

 

4 Direct comparison of targeted MRI-guided biopsy with systematic transrectal ultrasound-guided biopsy in patients with previous negative prostate biopsies Urologia Internationalis, September 19, 2014   

 

5 Over-expression of a poor prognostic marker in prostate cancer: AQP5 promotes cells growth and local invasion Full Text World Journal of Surgical Oncology, September 19, 2014    

 

6 Comparative effectiveness of robot-assisted versus open radical prostatectomy cancer control Full Text European Urology, September 19, 2014  

 

7 Correlation of quantitative diffusion-weighted and dynamic contrast-enhanced MRI parameters with prognostic factors in prostate cancer Journal of Medical Imaging and Radiation Oncology, September 19, 2014   

 

8 Reduced-FOV excitation decreases susceptibility artifact in diffusion-weighted MRI with endorectal coil for prostate cancer detection Magnetic Resonance Imaging, September 19, 2014

 

9 Autoantibodies against protein disulfide isomerase ER-60 are a diagnostic marker for low-grade testicular inflammation Human Reproduction, September 19, 2014    

 

10 Urinary incontinence during pregnancy: Is there a difference between first and third trimester? European Journal of Obstetrics & Gynecology and Reproductive Biology, September 19, 2014

 

11 DDX3X, the X homologue of AZFa gene DDX3Y, expresses a complex pattern of transcript variants only in the male germ line Molecular Human Reproduction, September 19, 2014

 

12 Risk of fracture after radical cystectomy and urinary diversion for bladder cancer Journal of Clinical Oncology, September 19, 2014    

 

13 Morphological alterations in protamine-deficient spermatozoa Human Reproduction, September 19, 2014   

 

14 Diagnosis and treatment of ureteral endometriosis: Study of 23 cases Full Text Urology Journal, September 19, 2014  

 

15 Neutralization of ASC improves sperm motility in men with spinal cord injury Human Reproduction, September 19, 2014

 

16 Regional variation in urinary catheter use and catheter-associated urinary tract infection: results from a national collaborative Infection Control and Hospital Epidemiology, September 19, 2014   

 

17 Testis sparing surgery in the treatment of bilateral testicular germ cell tumors and solitary testicle tumors: A single institution experience Journal of Surgical Oncology, September 19, 2014  

 

18 Matched-pair analysis of open versus laparoscopic nephroureterectomy for upper urinary tract urothelial cell carcinoma Urologia Internationalis, September 19, 2014    

 

19 Retroperitoneoscopic dismembered pyeloplasty for ureteropelvic junction obstruction: Modification of the procedure and our experience Full Text Urology Journal, September 19, 2014

 

20 Laparoendoscopic single-site adrenalectomy sans transumbilical approach: Initial experience in Japan Full Text Urology Journal, September 19, 2014

 

Source:MDLinx

ارسال شده توسط دکتر محمد هزارخانی در ساعت 10:29 قبل از ظهر |
Thu 18 Sep 2014

Original Article

Rebecca Smith-Bindman, M.D., Chandra Aubin, M.D., R.D.M.S., John Bailitz, M.D., Rimon N. Bengiamin, M.D., R.D.M.S., Carlos A. Camargo, Jr., M.D., Dr.P.H., Jill Corbo, M.D., R.D.M.S., Anthony J. Dean, M.D., Ruth B. Goldstein, M.D., Richard T. Griffey, M.D., M.P.H., Gregory D. Jay, M.D., Ph.D., Tarina L. Kang, M.D., Dana R. Kriesel, M.P.H., M.S., O. John Ma, M.D., Michael Mallin, M.D., William Manson, M.D., Joy Melnikow, M.D., M.P.H., Diana L. Miglioretti, Ph.D., Sara K. Miller, M.D., R.D.M.S., Lisa D. Mills, M.D., James R. Miner, M.D., Michelle Moghadassi, M.P.H., Vicki E. Noble, M.D., Gregory M. Press, M.D., Marshall L. Stoller, M.D., Victoria E. Valencia, M.P.H., Jessica Wang, M.D., Ralph C. Wang, M.D., and Steven R. Cummings, M.D.

N Engl J Med 2014; 371:1100-1110September 18, 2014DOI: 10.1056/NEJMoa1404446

Methods

In this multicenter, pragmatic, comparative effectiveness trial, we randomly assigned patients 18 to 76 years of age who presented to the emergency department with suspected nephrolithiasis to undergo initial diagnostic ultrasonography performed by an emergency physician (point-of-care ultrasonography), ultrasonography performed by a radiologist (radiology ultrasonography), or abdominal CT. Subsequent management, including additional imaging, was at the discretion of the physician. We compared the three groups with respect to the 30-day incidence of high-risk diagnoses with complications that could be related to missed or delayed diagnosis and the 6-month cumulative radiation exposure. Secondary outcomes were serious adverse events, related serious adverse events (deemed attributable to study participation), pain (assessed on an 11-point visual-analogue scale, with higher scores indicating more severe pain), return emergency department visits, hospitalizations, and diagnostic accuracy.

Results

A total of 2759 patients underwent randomization: 908 to point-of-care ultrasonography, 893 to radiology ultrasonography, and 958 to CT. The incidence of high-risk diagnoses with complications in the first 30 days was low (0.4%) and did not vary according to imaging method. The mean 6-month cumulative radiation exposure was significantly lower in the ultrasonography groups than in the CT group (P<0.001). Serious adverse events occurred in 12.4% of the patients assigned to point-of-care ultrasonography, 10.8% of those assigned to radiology ultrasonography, and 11.2% of those assigned to CT (P=0.50). Related adverse events were infrequent (incidence, 0.4%) and similar across groups. By 7 days, the average pain score was 2.0 in each group (P=0.84). Return emergency department visits, hospitalizations, and diagnostic accuracy did not differ significantly among the groups.

Conclusions

Initial ultrasonography was associated with lower cumulative radiation exposure than initial CT, without significant differences in high-risk diagnoses with complications, serious adverse events, pain scores, return emergency department visits, or hospitalizations. (Funded by the Agency for Healthcare Research and Quality.)

Source:The New England Journal of Medicine   Sep.18,2014

ارسال شده توسط دکتر محمد هزارخانی در ساعت 10:2 بعد از ظهر |
Thu 18 Sep 2014

Urology news  Sep.18,2014

R. Boguen1, P. Uribe1, F. Treulen1 andJ. V. Villegas1,2,*30 SEP2014/DOI: 10.1111/and.12167AndrologiaVolume 46, Issue 8, pages 943–947, October 2014

Summary

Sperm motility and vitality are decreased in male genital tract infection. Uropathogenic Escherichia coli (UPEC) are frequently associated with sperm parameter loss, but there are no reports to date regarding the effects of different E. coli isolates on human spermatozoa.

The aim of this work was to compare the effect in vitro of different E. coli isolates on human sperm parameters. Normal spermatozoa were incubated with E. coli isolated from nine men with urinary tract infection. After 1 h of incubation, sperm motility, vitality and mitochondrial membrane potential (ΔΨm) were measured.

The E. coli isolates were serotyped with specific antisera. Sperm motility was decreased with five of nine E. coli isolates. Two UPEC were typed as O6 strains, and they did not decrease sperm motility in the same experimental conditions as the other five isolates, despite the described high pathogenicity of the O6 strain in urogenital infections. Neither UPEC analysed affected vitality or ΔΨm.

UPEC isolates were shown to be heterogeneous in their effects, suggesting the need to characterise the pattern defining the pathogenicity of E. coli on human spermatozoa.

ارسال شده توسط دکتر محمد هزارخانی در ساعت 8:8 بعد از ظهر |
Thu 18 Sep 2014

News/Andrologia  Sep.18,2014

رابطه بین غلظت سرب وکادمیم با کیفیت اسپرم

 

N. Pant1,*, G. Kumar2, A. D. Upadhyay3, Y. K. Gupta2 andP. K. Chaturvedi1/16 SEP 2014DOI: 10.1111/and.12342© 2014 Blackwell Verlag GmbH/Andrologia

Summary

There are contrary reports of association of lead and cadmium with the decline in semen quality. This study evaluates whether seminal lead (Pb) and cadmium (Cd) at environmental concentration are associated with altered semen quality.

We conducted a study of healthy fertile and infertile men 20–43 years of age attending the Andrology Laboratory of Reproductive Biology Department for semen analysis. The semen analysis was carried out according to the WHO 2010 guidelines. Seminal lead and cadmium were estimated by ICP-AES. The lead and cadmium values were significantly higher in infertile subjects. A negative association between seminal lead or cadmium concentration and sperm concentration, sperm motility and per cent abnormal spermatozoa was found.

This study shows that exposure to Pb (5.29–7.25 μg dl−1) and cadmium (4.07–5.92 μg dl−1) might affect semen profile in men. Age, diet, smoking and tobacco chewing habits may have an influence on the increase in exposure to Pb and Cd in the individual subjects.

ارسال شده توسط دکتر محمد هزارخانی در ساعت 7:53 بعد از ظهر |
Thu 18 Sep 2014

 

Correlation between lead and cadmium concentration and semen quality

N. Pant, G. Kumar, A. D. Upadhyay, Y. K. Gupta and P. K. Chaturvedi

Article first published online: 16 SEP 2014 | DOI: 10.1111/and.12342

Diabetes mellitus and late-onset hypogonadism: the role of Glu298Asp endothelial nitric oxide synthase polymorphism

N. delli Muti, G. Tirabassi, G. R. Lamonica, A. Lenzi and G. Balercia

Article first published online: 16 SEP 2014 | DOI: 10.1111/and.12339

Testicular resistive index determined by Doppler ultrasonography in men with spinal cord injury – a case series

J. Krebs, K. Göcking and J. Pannek

Article first published online: 16 SEP 2014 | DOI: 10.1111/and.12334

Effects of chronic tramadol administration on testicular tissue in rats: an experimental study

R. B. Abdellatief, D. A. Elgamal and E. E. M. Mohamed

Article first published online: 16 SEP 2014 | DOI: 10.1111/and.12316

A human morphologically normal spermatozoon may have noncondensed chromatin

F. Boitrelle, M. Pagnier, Y. Athiel, N. Swierkowski-Blanchard, A. Torre, L. Alter, C. Muratorio, F. Vialard, M. Albert and J. Selva

Article first published online: 15 SEP 2014 | DOI: 10.1111/and.12341

Men regret anabolic steroid use due to a lack of comprehension regarding the consequences on future fertility

J. R. Kovac, J. Scovell, R. Ramasamy, S. Rajanahally, R. M. Coward, R. P. Smith and L. I. Lipshultz

Article first published online: 15 SEP 2014 | DOI: 10.1111/and.12340

Review on the screening of semen by hypo-osmotic swelling test

M. Zubair, M. Ahmad and H. Jamil

Article first published online: 15 SEP 2014 | DOI: 10.1111/and.12335

Experimentally induced hyperthyroidism influences oxidant and antioxidant status and impairs male gonadal functions in adult rats

M. E. Asker, W. A. Hassan and A. M. El-Kashlan

Article first published online: 13 SEP 2014 | DOI: 10.1111/and.12312

Intracellular calcium concentration of corpus cavernosum smooth muscle cells is decreased by the overexpression of PnNOS gene in adipose tissue-derived stem cells

J. Chen, Z. Hu, L. Zhuan, H. Xiao, Y. Zhang and J. Yang

Article first published online: 13 SEP 2014 | DOI: 10.1111/and.12323

Relationship between human spermatozoa–hyaluronan-binding assay, conventional semen parameters and fertilisation rates in intracytoplasmic spermatozoa injection

A. D. Esterhuizen, D. R. Franken, E. Bosman, F. A. Rodrigues, J. H. Van Rensburg, J. A. M. Van Schouwenburg and C. Lombaard

Article first published online: 13 SEP 2014 | DOI: 10.1111/and.12326

A simple sperm nuclear vacuole assay with propidium iodide

W.-J. Zhu and J. Li

Article first published online: 13 SEP 2014 | DOI: 10.1111/and.12328

Hesperidin protects testicular and spermatological damages induced by cisplatin in rats

K. Kaya, O. Ciftci, A. Cetin, H. Doğan and N. Başak

Article first published online: 13 SEP 2014 | DOI: 10.1111/and.12332

Magnetic activated cell sorting: an effective method for reduction of sperm DNA fragmentation in varicocele men prior to assisted reproductive techniques

T. Degheidy, H. Abdelfattah, A. Seif, F. K. Albuz, S. Gazi and S. Abbas

Article first published online: 11 SEP 2014 | DOI: 10.1111/and.12343

Presence of aerobic micro-organisms and their influence on basic semen parameters in infertile men

E. Filipiak, K. Marchlewska, E. Oszukowska, R. Walczak-Jedrzejowska, A. Swierczynska-Cieplucha, K. Kula and J. Slowikowska-Hilczer

Article first published online: 11 SEP 2014 | DOI: 10.1111/and.12338

Xenotransplantation assessment: morphometric study of human spermatogonial stem cells in recipient mouse testes

T. Mirzapour, M. Movahedin, M. Koruji and M. R. Nowroozi

Article first published online: 11 SEP 2014 | DOI: 10.1111/and.12310

ارسال شده توسط دکتر محمد هزارخانی در ساعت 7:23 بعد از ظهر |
Thu 18 Sep 2014

 

1 Effect of treatment delay on survival in patients with cervical cancer: A historical cohort study International Journal of Gynecological Cancer, September 18, 2014    

 

2 Placental concentrations of bisphenol A and birth weight from births in the Southeastern U.S. Placenta, September 18, 2014  

 

3 Adult physical, sexual, and emotional abuse and postpartum depression, a population based, prospective study of 53,065 women in the Norwegian Mother and Child Cohort Study Full Text BMC Pregnancy and Childbirth, September 18, 2014      

 

4 Identification of women at high risk for severe perineal lacerations European Journal of Obstetrics & Gynecology and Reproductive Biology, September 18, 2014   

 

5 Socioeconomic disparities in prepregnancy BMI and impact on maternal and neonatal outcomes and postpartum weight retention: The EFHL longitudinal birth cohort study Full Text BMC Pregnancy and Childbirth, September 18, 2014     

 

6 Intrapartum magnesium sulfate and need for intensive delivery room resuscitation ADC Fetal & Neonatal Edition, September 18, 2014    

 

7 Mode of childbirth and long-term outcomes in women with inflammatory bowel diseases Digestive Diseases and Sciences, September 18, 2014   

 

8 Hemodynamic and metabolic effects of estrogen plus progestin therapy in hypertensive postmenopausal women treated with an ACE-inhibitor or a diuretic Clinical Research in Cardiology, September 18, 2014   

 

9 Mutation analysis of PALB2 in BRCA1 and BRCA2-negative breast and/or ovarian cancer families from Eastern Ontario, Canada Full Text Hereditary Cancer in Clinical Practice, September 18, 2014  

 

10 Increased risk of serious bacterial infections due to maternal immunosuppression in HIV-exposed uninfected infants in a European country Clinical Infectious Diseases, September 18, 2014  

 

11 Improving women's diet quality preconceptionally and during gestation: effects on birth weight and prevalence of low birth weight—a randomized controlled efficacy trial in India (Mumbai Maternal Nutrition Project) American Journal of Clinical Nutrition, September 18, 2014    

 

12 Diagnostic significance of diffusion-weighted MRI in patients with cervical cancer: A meta-analysis Tumor Biology, September 18, 2014    

 

13 Effects of switching from anastrozole to letrozole, due to reimbursement policy, on the outcome of breast cancer therapy Full Text Breast Cancer: Targets and Therapy, September 18, 2014   

 

14 Effects of maternal smoking on the placental expression of genes related to angiogenesis and apoptosis during the first trimester PLOS ONE, September 18, 2014    

 

15 Body size and risk of spontaneous abortion among Danish pregnancy planners Paediatric and Perinatal Epidemiology, September 18, 2014    

 

16 The relationship between health-related fitness and quality of life in postmenopausal women from Southern Taiwan Full Text Clinical Interventions in Aging, September 18, 2014    

 

17 Mastopexy and reduction mammoplasty pedicles and skin resection patterns Full Text Plastic and Reconstructive Surgery - Global Open, September 18, 2014   

 

18 Developmental outcomes in young children born to mothers with West Nile illness during pregnancy Birth Defects Research Part A: Clinical and Molecular Teratology, September 18, 2014

 

19 Genetic studies of ANKRD6 as a molecular switch between Wnt signaling pathways in human neural tube defects Birth Defects Research Part A: Clinical and Molecular Teratology, September 18, 2014

 

20 Periconceptional parental conditions and perimembranous ventricular septal defects in the offspring Birth Defects Research Part A: Clinical and Molecular Teratology, September 18, 2014

ارسال شده توسط دکتر محمد هزارخانی در ساعت 6:51 بعد از ظهر |
Thu 18 Sep 2014

 

1 The role of focal therapy in the management of localised prostate cancer: A systematic review Full Text European Urology, September 18, 2014   

 

2 Association of variants in genes related to the immune response and obesity with BPH in CLUE II Prostate Cancer & Prostatic Diseases, September 18, 2014      

 

3 The influence of prior abiraterone treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer Full Text European Urology, September 18, 2014  

 

4 Polymorphisms at long non-coding RNAs and prostate cancer risk in an Eastern Chinese population Prostate Cancer & Prostatic Diseases, September 18, 2014    

 

5 Influence of radical prostatectomy for prostate cancer on work status and working life 3 years after surgery Journal of Cancer Survivorship, September 18, 2014   

 

6 Coupling of prostate and thyroid cancer diagnoses in the United States Annals of Surgical Oncology, September 18, 2014    

 

7 Salvage pelvic lymph node dissection after radical prostatectomy for biochemical and lymph node recurrence Urologia Internationalis, September 18, 2014    

 

8 Stereotactic body radiotherapy for organ-confined prostate cancer Full Text Translational Cancer Research , September 18, 2014      

 

9 Ureteroscopy for stone disease in the paediatric population - A systematic review BJU International, September 18, 2014    

 

10 Medical therapy in overactive bladder of the elderly Current Bladder Dysfunction Reports, September 18, 2014      

 

11 Identification of frequent differentially methylated region in sporadic bladder cancers Urologia Internationalis, September 18, 2014  

 

12 Analysis of renal anomalies in VACTERL association Birth Defects Research Part A: Clinical and Molecular Teratology, September 18, 2014

 

13 Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker Investigative Radiology, September 18, 2014   

 

14 Ten year experience of retroperitoneal laparoscopic resection for pheochromocytomas: A dual-centre study of 72 cases World Journal of Urology, September 18, 2014    

 

15 ICS teaching module: Analysis of voiding, pressure flow analysis (basic module) Neurourology and Urodynamics, September 18, 2014

 

16 Voiding dysfunction in patients with neuromyelitis optica spectrum disorders Neurourology and Urodynamics, September 18, 2014      

 

17 The value of surgical release after obstructive anti-incontinence surgery: An aid for clinical decision making Neurourology and Urodynamics, September 18, 2014

 

18 Photobiomodulation with light-emitting diodes improves sperm motility in men with asthenozoospermia Lasers in Medical Science, September 18, 2014     

 

19 Presence of aerobic micro-organisms and their influence on basic semen parameters in infertile men Andrologia, September 18, 2014    

 

20 Magnetic activated cell sorting: An effective method for reduction of sperm DNA fragmentation in varicocele men prior to assisted reproductive techniques Andrologia, September 18, 2014  

 

21Finding New Genetic Links to Prostate Cancer

Sep. 17, 2014 — 23 new regions of the genome have been discovered that influence the risk for developing prostate cancer, according to a study. Prostate cancer is the most common non-skin cancer in American men. ..  

  

22Study Identifies When and How Much Various Prostate Cancer Treatments Will Impact Urinary and Sexual Functioning

Sep. 16, 2014 — Men with prostate cancer may one day be able to predict when and how much various treatments will impact their urinary and sexual functioning, thanks in part to new ...  

 

23New Gene Research Helps Pinpoint Prostate Cancer Risk

Sep. 16, 2014 — A consortia of research hubs around the world encompassing 150 researchers has analysed more than 10 million genetic markers in 80,000 men with prostate cancer. "We now have 100 genetic regions ...   

 

24Most Prostate Cancer Patients Surveyed Five Years After Vessel-Sparing Radiation Therapy Report Preserved Sexual Function

Sep. 16, 2014 — A comparison of five-year sexual function outcomes, as reported by patients treated with external beam radiotherapy (EBRT) versus combination EBRT plus brachytherapy, indicates that the utilization ...   

 

25Long-Term Androgen Deprivation Therapy Combined With High-Dose Radiation Therapy for Prostate Cancer Improves Biochemical Control and Survival Rates

Sep. 16, 2014 — Prostate cancer patients who receive high-dose radiation therapy (HDRT) followed by a longer period of hormone suppression therapy, or androgen deprivation therapy (ADT), have higher five-year ...   

26Certain Form of Baldness at Age 45 Linked to Higher Risk for Aggressive Prostate Cancer

Sep. 15, 2014 — A new, large cohort analysis from the prospective Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, indicates that men who had moderate baldness affecting both the front and the ...   

 

27Shorter Course of Androgen Deprivation Therapy for High-Risk Prostate Cancer Patients Yields Improved Quality of Life

Sep. 15, 2014 — High-risk prostate cancer patients who receive radiation therapy (RT) and an 18-month course of androgen deprivation therapy (ADT) recover a normal testosterone level in a shorter amount of time ...  

ارسال شده توسط دکتر محمد هزارخانی در ساعت 6:33 بعد از ظهر |